• Provide strategic oversight and end-to-end operational leadership for global Phase 3 asthma studies and related development activities. • Translate program strategy into comprehensive, executable operational plans aligned with regulatory, scientific, and corporate objectives. • Accountable for study timelines, budgets, resource allocation, quality metrics, and overall delivery. • Lead scenario planning, risk forecasting, and mitigation strategies at the program level. • Partner with Clinical Development leadership to inform portfolio-level planning and decision-making. • Directly manage and develop Clinical Operations staff (e.g., Clinical Trial Leads and/or Clinical Trial Managers). • Recruit, hire, onboard, and retain top talent to support late-stage clinical development. • Set performance expectations, conduct evaluations, provide coaching, and support career development. • Build a culture of accountability, collaboration, and operational excellence. • Lead multidisciplinary study teams across Clinical Operations, Data Management, Biostatistics, Safety, Regulatory, Medical, Quality, and CMC. • Act as a primary point of accountability across internal stakeholders, CRO partners, and external vendors. • Enable effective decision-making, timely escalation, and transparent communication across teams. • Oversee global study startup, site strategy, enrollment execution, monitoring approaches, and patient engagement initiatives. • Ensure compliance with ICH-GCP, global regulatory requirements, and internal SOPs. • Provide oversight of study budgets, vendor performance, and quality metrics. • Establish performance metrics and drive continuous improvement across external partnerships. • Lead inspection readiness strategy and support regulatory inspections. • Drive proactive issue identification, risk management, and CAPA oversight. • Contribute to Clinical Operations strategy, infrastructure development, and process optimization. • Champion innovation in trial execution, including digital tools, decentralized approaches, and patient-focused strategies. • Share best practices and help define standards across the clinical operations organization.